MedTerms Medical Dictionary

Mast cell: A connective tissue cell whose normal function is unknown, the mast cell is frequently injured during allergic reactions, releasing strong chemicals including histamine into the tissues and blood that are very irritating and cause itching, swelling, and fluid leaking from cells. These allergic chemicals can also cause muscle spasm and lead to lung and throat tightening as is found in asthma and loss of voice.

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